An adapted consensus protein design strategy for identifying globally optimal biotherapeutics

Biotherapeutic optimization, whether to improve general properties or to engineer specific attributes, is a time-consuming process with uncertain outcomes. Conversely, Consensus Protein Design has been shown to be a viable approach to enhance protein stability while retaining function. In adapting t...

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Detalles Bibliográficos
Autores principales: Liu, Yanyun, Tsang, Kenny, Mays, Michelle, Hansen, Gale, Chiecko, Jeffrey, Crames, Maureen, Wei, Yangjie, Zhou, Weijie, Fredrick, Chase, Hu, James, Liu, Dongmei, Gebhard, Douglas, Huang, Zhong-Fu, Datar, Akshita, Kronkaitis, Anthony, Gueneva-Boucheva, Kristina, Seeliger, Daniel, Han, Fei, Sen, Saurabh, Kasturirangan, Srinath, Scheer, Justin M., Nixon, Andrew E., Panavas, Tadas, Marlow, Michael S., Kumar, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135432/
https://www.ncbi.nlm.nih.gov/pubmed/35613320
http://dx.doi.org/10.1080/19420862.2022.2073632

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