Cargando…

Research Advances on Anti-Cancer Natural Products

Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Meng, Jin, Jie, Zhao, Dong, Rong, Zheng, Cao, Lu-Qi, Li, Ai-Hong, Sun, Xiao-Ying, Jia, Li-Yi, Wang, Yin-Di, Huang, Ling, Li, Yi-Heng, He, Zhong-Jing, Li, Long, Ma, Rui-Kang, Lv, Yi-Fan, Shao, Ke-Ke, Cao, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135452/
https://www.ncbi.nlm.nih.gov/pubmed/35646647
http://dx.doi.org/10.3389/fonc.2022.866154
_version_ 1784713962232741888
author Guo, Meng
Jin, Jie
Zhao, Dong
Rong, Zheng
Cao, Lu-Qi
Li, Ai-Hong
Sun, Xiao-Ying
Jia, Li-Yi
Wang, Yin-Di
Huang, Ling
Li, Yi-Heng
He, Zhong-Jing
Li, Long
Ma, Rui-Kang
Lv, Yi-Fan
Shao, Ke-Ke
Cao, Hui-Ling
author_facet Guo, Meng
Jin, Jie
Zhao, Dong
Rong, Zheng
Cao, Lu-Qi
Li, Ai-Hong
Sun, Xiao-Ying
Jia, Li-Yi
Wang, Yin-Di
Huang, Ling
Li, Yi-Heng
He, Zhong-Jing
Li, Long
Ma, Rui-Kang
Lv, Yi-Fan
Shao, Ke-Ke
Cao, Hui-Ling
author_sort Guo, Meng
collection PubMed
description Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products were categorized into eight classes according to their chemical structures, including alkaloids, terpenoids and volatile oils, inorganic salts, phenylpropanoids, flavonoids and isoflavones, quinone, saponins and polysaccharides. The review focused on the latest advances in anti-cancer activity of representative natural products for every class. Additionally, anti-cancer molecular mechanism and derivatization of natural products were summarized in detail, which would provide new core structures and new insights for anti-cancer new drug development.
format Online
Article
Text
id pubmed-9135452
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-91354522022-05-27 Research Advances on Anti-Cancer Natural Products Guo, Meng Jin, Jie Zhao, Dong Rong, Zheng Cao, Lu-Qi Li, Ai-Hong Sun, Xiao-Ying Jia, Li-Yi Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Cao, Hui-Ling Front Oncol Oncology Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products were categorized into eight classes according to their chemical structures, including alkaloids, terpenoids and volatile oils, inorganic salts, phenylpropanoids, flavonoids and isoflavones, quinone, saponins and polysaccharides. The review focused on the latest advances in anti-cancer activity of representative natural products for every class. Additionally, anti-cancer molecular mechanism and derivatization of natural products were summarized in detail, which would provide new core structures and new insights for anti-cancer new drug development. Frontiers Media S.A. 2022-05-06 /pmc/articles/PMC9135452/ /pubmed/35646647 http://dx.doi.org/10.3389/fonc.2022.866154 Text en Copyright © 2022 Guo, Jin, Zhao, Rong, Cao, Li, Sun, Jia, Wang, Huang, Li, He, Li, Ma, Lv, Shao and Cao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Guo, Meng
Jin, Jie
Zhao, Dong
Rong, Zheng
Cao, Lu-Qi
Li, Ai-Hong
Sun, Xiao-Ying
Jia, Li-Yi
Wang, Yin-Di
Huang, Ling
Li, Yi-Heng
He, Zhong-Jing
Li, Long
Ma, Rui-Kang
Lv, Yi-Fan
Shao, Ke-Ke
Cao, Hui-Ling
Research Advances on Anti-Cancer Natural Products
title Research Advances on Anti-Cancer Natural Products
title_full Research Advances on Anti-Cancer Natural Products
title_fullStr Research Advances on Anti-Cancer Natural Products
title_full_unstemmed Research Advances on Anti-Cancer Natural Products
title_short Research Advances on Anti-Cancer Natural Products
title_sort research advances on anti-cancer natural products
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135452/
https://www.ncbi.nlm.nih.gov/pubmed/35646647
http://dx.doi.org/10.3389/fonc.2022.866154
work_keys_str_mv AT guomeng researchadvancesonanticancernaturalproducts
AT jinjie researchadvancesonanticancernaturalproducts
AT zhaodong researchadvancesonanticancernaturalproducts
AT rongzheng researchadvancesonanticancernaturalproducts
AT caoluqi researchadvancesonanticancernaturalproducts
AT liaihong researchadvancesonanticancernaturalproducts
AT sunxiaoying researchadvancesonanticancernaturalproducts
AT jialiyi researchadvancesonanticancernaturalproducts
AT wangyindi researchadvancesonanticancernaturalproducts
AT huangling researchadvancesonanticancernaturalproducts
AT liyiheng researchadvancesonanticancernaturalproducts
AT hezhongjing researchadvancesonanticancernaturalproducts
AT lilong researchadvancesonanticancernaturalproducts
AT maruikang researchadvancesonanticancernaturalproducts
AT lvyifan researchadvancesonanticancernaturalproducts
AT shaokeke researchadvancesonanticancernaturalproducts
AT caohuiling researchadvancesonanticancernaturalproducts