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Research Advances on Anti-Cancer Natural Products
Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products wer...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135452/ https://www.ncbi.nlm.nih.gov/pubmed/35646647 http://dx.doi.org/10.3389/fonc.2022.866154 |
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author | Guo, Meng Jin, Jie Zhao, Dong Rong, Zheng Cao, Lu-Qi Li, Ai-Hong Sun, Xiao-Ying Jia, Li-Yi Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Cao, Hui-Ling |
author_facet | Guo, Meng Jin, Jie Zhao, Dong Rong, Zheng Cao, Lu-Qi Li, Ai-Hong Sun, Xiao-Ying Jia, Li-Yi Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Cao, Hui-Ling |
author_sort | Guo, Meng |
collection | PubMed |
description | Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products were categorized into eight classes according to their chemical structures, including alkaloids, terpenoids and volatile oils, inorganic salts, phenylpropanoids, flavonoids and isoflavones, quinone, saponins and polysaccharides. The review focused on the latest advances in anti-cancer activity of representative natural products for every class. Additionally, anti-cancer molecular mechanism and derivatization of natural products were summarized in detail, which would provide new core structures and new insights for anti-cancer new drug development. |
format | Online Article Text |
id | pubmed-9135452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91354522022-05-27 Research Advances on Anti-Cancer Natural Products Guo, Meng Jin, Jie Zhao, Dong Rong, Zheng Cao, Lu-Qi Li, Ai-Hong Sun, Xiao-Ying Jia, Li-Yi Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Cao, Hui-Ling Front Oncol Oncology Malignant tumors seriously threaten people’s health and life worldwide. Natural products, with definite pharmacological effects and known chemical structures, present dual advantages of Chinese herbs and chemotherapeutic drug. Some of them exhibit favorable anti-cancer activity. Natural products were categorized into eight classes according to their chemical structures, including alkaloids, terpenoids and volatile oils, inorganic salts, phenylpropanoids, flavonoids and isoflavones, quinone, saponins and polysaccharides. The review focused on the latest advances in anti-cancer activity of representative natural products for every class. Additionally, anti-cancer molecular mechanism and derivatization of natural products were summarized in detail, which would provide new core structures and new insights for anti-cancer new drug development. Frontiers Media S.A. 2022-05-06 /pmc/articles/PMC9135452/ /pubmed/35646647 http://dx.doi.org/10.3389/fonc.2022.866154 Text en Copyright © 2022 Guo, Jin, Zhao, Rong, Cao, Li, Sun, Jia, Wang, Huang, Li, He, Li, Ma, Lv, Shao and Cao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Guo, Meng Jin, Jie Zhao, Dong Rong, Zheng Cao, Lu-Qi Li, Ai-Hong Sun, Xiao-Ying Jia, Li-Yi Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Cao, Hui-Ling Research Advances on Anti-Cancer Natural Products |
title | Research Advances on Anti-Cancer Natural Products |
title_full | Research Advances on Anti-Cancer Natural Products |
title_fullStr | Research Advances on Anti-Cancer Natural Products |
title_full_unstemmed | Research Advances on Anti-Cancer Natural Products |
title_short | Research Advances on Anti-Cancer Natural Products |
title_sort | research advances on anti-cancer natural products |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135452/ https://www.ncbi.nlm.nih.gov/pubmed/35646647 http://dx.doi.org/10.3389/fonc.2022.866154 |
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