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Vaccine-induced T-cell responses against SARS-CoV-2 and its Omicron variant in patients with B cell–depleted lymphoma after CART therapy
Patients receiving CD19 CAR T-cell therapy for relapsed/refractory lymphoma experience prolonged and profound B-cell aplasia and hypogammaglobulinemia, placing them at a higher risk for severe COVID-19. Independently, Oh et al and Atanackovic et al demonstrate that despite attenuated humoral respons...
Autores principales: | Atanackovic, Djordje, Luetkens, Tim, Omili, Destiny, Iraguha, Thierry, Lutfi, Forat, Hardy, Nancy M., Fan, Xiaoxuan, Avila, Stephanie V., Saharia, Kapil K., Husson, Jennifer S., Niederhaus, Silke V., Margiotta, Philip, Lee, Seung T., Law, Jennie Y., Mannuel, Heather D., Vander Mause, Erica, Bauman, Sherri, Lesho, Patricia, Hankey, Kim, Baddley, John, Kocoglu, Mehmet, Yared, Jean A., Rapoport, Aaron P., Dahiya, Saurabh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135504/ https://www.ncbi.nlm.nih.gov/pubmed/35537186 http://dx.doi.org/10.1182/blood.2022016175 |
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