Cargando…

Levetiracetam Attenuates the Spinal Cord Injury Induced by Acute Trauma via Suppressing the Expression of Perforin

The spinal cord injury (SCI) is one of the major reasons causing the motor dysfunctions of the patients. At present, few therapeutic strategies can effectively improve the symptom of SCI. Levetiracetam has been confirmed to alleviate the injury of nerve cells, while its functions in SCI remains uncl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Hong, Huang, Jiaqiang, Liu, Jian, Zhang, Hua, Chen, Dawei, Zhang, Wen, Zhou, Xianghong, Wei, Zhouyang, Liu, Zhaoxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135510/ https://www.ncbi.nlm.nih.gov/pubmed/35633929 http://dx.doi.org/10.1155/2022/7218666

Ejemplares similares

Retracted: Levetiracetam Attenuates the Spinal Cord Injury Induced by Acute Trauma via Suppressing the Expression of Perforin
por: Methods in Medicine, Computational and Mathematical
Publicado: (2022)

Levetiracetam treatment leads to functional recovery after thoracic or cervical injuries of the spinal cord
por: Lima, Rui, et al.
Publicado: (2021)

Levetiracetam attenuates diabetes-associated cognitive impairment and microglia polarization by suppressing neuroinflammation
por: Zhang, Yun-yun, et al.
Publicado: (2023)

Perforin deficiency attenuates collagen-induced arthritis
por: Bauer, Kristin, et al.
Publicado: (2005)

MK801 attenuates secondary injury in a mouse experimental compression model of spinal cord trauma
por: Esposito, Emanuela, et al.
Publicado: (2011)

Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke
por: Pan, Yuhualei, et al.
Publicado: (2021)

Suppression of Myoclonus in Corticobasal Degeneration by Levetiracetam
por: Cho, Jae Wook, et al.
Publicado: (2014)

Ruxolitinib attenuates secondary injury after traumatic spinal cord injury
por: Qian, Zhan-Yang, et al.
Publicado: (2022)

Spinal Cord Injury Without Radiological Abnormality in Adult Thoracic Spinal Trauma
por: Khatri, Kavin, et al.
Publicado: (2014)

Spinal cord injury and its association with blunt head trauma
por: Paiva, Wellingson S, et al.
Publicado: (2011)

The pathophysiology of spinal cord trauma /
por: Osterholm, Jewell L.
Publicado: (1978)

Perforin and hematological cancer
por: Covas, Dimas Tadeu
Publicado: (2011)

Perforin Acts as an Immune Regulator to Prevent the Progression of NAFLD
por: Wang, Qian, et al.
Publicado: (2020)

Olprinone Attenuates the Acute Inflammatory Response and Apoptosis after Spinal Cord Trauma in Mice
por: Esposito, Emanuela, et al.
Publicado: (2010)

Granzyme-A deficiency attenuates experimental osteoarthritis in mice, but perforin deficiency does not
por: Calvo, Jorge, et al.
Publicado: (2023)

Recent advances in managing a spinal cord injury secondary to trauma
por: Ahuja, Christopher S., et al.
Publicado: (2016)

Edema after CNS Trauma: A Focus on Spinal Cord Injury
por: Seblani, Mostafa, et al.
Publicado: (2023)

Resveratrol Can Attenuate Astrocyte Activation to Treat Spinal Cord Injury by Inhibiting Inflammatory Responses
por: Fan, Ruihua, et al.
Publicado: (2021)

Efficacy of levetiracetam combined with sodium valproate on pediatric epilepsy and its effect on serum miR-106b in children
por: Zhao, Jiaqiang, et al.
Publicado: (2019)

Melatonin for the treatment of spinal cord injury
por: Zhang, Yan, et al.
Publicado: (2018)

Multifunctional biomimetic spinal cord: New approach to repair spinal cord injuries
por: Liu, Yang, et al.
Publicado: (2017)

Delayed presentation of spinal cord trauma
por: Gupta, Babita, et al.
Publicado: (2011)

SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc
por: Jiang, Tao, et al.
Publicado: (2023)

The pore conformation of lymphocyte perforin
por: Ivanova, Marina E., et al.
Publicado: (2022)

Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats
por: Ge, Li, et al.
Publicado: (2017)

Administration of Levetiracetam in Traumatic Brain Injury: Is it Warranted?
por: DJohn, Jason, et al.
Publicado: (2020)

Zafirlukast in combination with pseudohypericin attenuates spinal cord injury and motor function in experimental mice
por: Chen, Xiao-Gang, et al.
Publicado: (2018)

Adenosine leakage from perforin-burst extracellular vesicles inhibits perforin secretion by cytotoxic T-lymphocytes
por: Tadokoro, Hiroko, et al.
Publicado: (2020)

IVIg attenuates complement and improves spinal cord injury outcomes in mice
por: Brennan, Faith H., et al.
Publicado: (2016)

Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice
por: Jiang, Wu, et al.
Publicado: (2017)

Pretreatment with AQP4 and NKCC1 Inhibitors Concurrently Attenuated Spinal Cord Edema and Tissue Damage after Spinal Cord Injury in Rats
por: Yan, Xiaodong, et al.
Publicado: (2018)

Cervical Spine Trauma and Spinal Cord Injury Recommendations of WFNS Spine Committee
por: Zileli, Mehmet, et al.
Publicado: (2020)

Patterns and Predictors of Firearm-related Spinal Cord Injuries in Adult Trauma Patients
por: Mahmassani, Dina, et al.
Publicado: (2021)

Suppression of Superficial Microglial Activation by Spinal Cord Stimulation Attenuates Neuropathic Pain Following Sciatic Nerve Injury in Rats
por: Shinoda, Masamichi, et al.
Publicado: (2020)

Resveratrol, an antioxidant, protects spinal cord injury in rats by suppressing MAPK pathway
por: Fu, Song, et al.
Publicado: (2018)

Electroacupuncture Treatment Suppresses Transcription Factor IRF8 in Spinal Cord of Rats with Spared Nerve Injury
por: Wang, Ying, et al.
Publicado: (2020)

A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
por: Jian, Yunbo, et al.
Publicado: (2022)

Application and progress of three‐dimensional bioprinting in spinal cord injury
por: Xia, Qiu‐Qiu, et al.
Publicado: (2021)

Pyroptosis in spinal cord injury
por: Yin, Jian, et al.
Publicado: (2022)

Therapeutic effect of umbilical cord blood cells on spinal cord injury
por: Zhang, Jun‐Yan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qcsquaor573g5qkm6qlhflg590