Whole-genome sequencing reveals novel ethnicity-specific rare variants associated with Alzheimer’s disease

Alzheimer’s disease (AD) is the most common multifactorial neurodegenerative disease among elderly people. Genome-wide association studies (GWAS) have been highly successful in identifying genetic risk factors. However, GWAS investigate common variants, which tend to have small effect sizes, and rar...

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Detalles Bibliográficos
Autores principales: Shigemizu, Daichi, Asanomi, Yuya, Akiyama, Shintaro, Mitsumori, Risa, Niida, Shumpei, Ozaki, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135624/
https://www.ncbi.nlm.nih.gov/pubmed/35264725
http://dx.doi.org/10.1038/s41380-022-01483-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135624/
https://www.ncbi.nlm.nih.gov/pubmed/35264725
http://dx.doi.org/10.1038/s41380-022-01483-0

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