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Whole-genome sequencing reveals novel ethnicity-specific rare variants associated with Alzheimer’s disease
Alzheimer’s disease (AD) is the most common multifactorial neurodegenerative disease among elderly people. Genome-wide association studies (GWAS) have been highly successful in identifying genetic risk factors. However, GWAS investigate common variants, which tend to have small effect sizes, and rar...
Autores principales: | Shigemizu, Daichi, Asanomi, Yuya, Akiyama, Shintaro, Mitsumori, Risa, Niida, Shumpei, Ozaki, Kouichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135624/ https://www.ncbi.nlm.nih.gov/pubmed/35264725 http://dx.doi.org/10.1038/s41380-022-01483-0 |
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