Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca(2+) signaling

The cellular mechanisms of autism spectrum disorder (ASD) are poorly understood. Cumulative evidence suggests that abnormal synapse function underlies many features of this disease. Astrocytes regulate several key neuronal processes, including the formation of synapses and the modulation of synaptic...

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Detalles Bibliográficos
Autores principales: Allen, Megan, Huang, Ben S., Notaras, Michael J., Lodhi, Aiman, Barrio-Alonso, Estibaliz, Lituma, Pablo J., Wolujewicz, Paul, Witztum, Jonathan, Longo, Francesco, Chen, Maoshan, Greening, David W., Klann, Eric, Ross, M. Elizabeth, Liston, Conor, Colak, Dilek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135629/
https://www.ncbi.nlm.nih.gov/pubmed/35365802
http://dx.doi.org/10.1038/s41380-022-01486-x

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