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Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial

Aim: To assess the results of a phase I/IIa open-label dose-escalation clinical trial of 5-day repeated intramuscular administration of pitavastatin-incorporated poly (lactic-co-glycolic acid) nanoparticles (NK-104-NP) in patients with chronic limb threatening ischemia (CLTI). Methods: NK-104-NP was...

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Detalles Bibliográficos
Autores principales: Matsumoto, Takuya, Yoshino, Shinichiro, Furuyama, Tadashi, Morisaki, Koichi, Nakano, Kaku, Koga, Jun-ichiro, Maehara, Yoshihiko, Komori, Kimihiro, Mori, Masaki, Egashira, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135659/
https://www.ncbi.nlm.nih.gov/pubmed/33907060
http://dx.doi.org/10.5551/jat.58941