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Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial
Aim: To assess the results of a phase I/IIa open-label dose-escalation clinical trial of 5-day repeated intramuscular administration of pitavastatin-incorporated poly (lactic-co-glycolic acid) nanoparticles (NK-104-NP) in patients with chronic limb threatening ischemia (CLTI). Methods: NK-104-NP was...
Autores principales: | Matsumoto, Takuya, Yoshino, Shinichiro, Furuyama, Tadashi, Morisaki, Koichi, Nakano, Kaku, Koga, Jun-ichiro, Maehara, Yoshihiko, Komori, Kimihiro, Mori, Masaki, Egashira, Kensuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Atherosclerosis Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135659/ https://www.ncbi.nlm.nih.gov/pubmed/33907060 http://dx.doi.org/10.5551/jat.58941 |
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