Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation

Tumor cells with diverse phenotypes and biological behaviors are influenced by stromal cells through secretory factors or direct cell-cell contact. Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia with fibroblasts as the major cell type. In the present study, we obse...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ing, Chang, Chin-Chun, Hsu, Min-Fen, Jeng, Yung-Ming, Tien, Yu-Wen, Chang, Ming-Chu, Chang, Yu-Ting, Hu, Chun-Mei, Lee, Wen-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135720/
https://www.ncbi.nlm.nih.gov/pubmed/35618735
http://dx.doi.org/10.1038/s41467-022-30638-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135720/
https://www.ncbi.nlm.nih.gov/pubmed/35618735
http://dx.doi.org/10.1038/s41467-022-30638-4

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