SARS-CoV-2 ORF7a potently inhibits the antiviral effect of the host factor SERINC5

Serine Incorporator 5 (SERINC5), a cellular multipass transmembrane protein that is involved in sphingolipid and phosphatydilserine biogenesis, potently restricts a number of retroviruses, including Human Immunodeficiency Virus (HIV). SERINC5 is incorporated in the budding virions leading to the inh...

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Detalles Bibliográficos
Autores principales: Timilsina, Uddhav, Umthong, Supawadee, Ivey, Emily B., Waxman, Brandon, Stavrou, Spyridon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135752/
https://www.ncbi.nlm.nih.gov/pubmed/35618710
http://dx.doi.org/10.1038/s41467-022-30609-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135752/
https://www.ncbi.nlm.nih.gov/pubmed/35618710
http://dx.doi.org/10.1038/s41467-022-30609-9

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