Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions

Development of the gastrointestinal system occurs after gut tube closure, guided by spatial and temporal control of gene expression. However, it remains unclear what forces regulate these spatiotemporal gene expression patterns. Here we perform single-cell chromatin profiling of the primitive gut tu...

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Detalles Bibliográficos
Autores principales: Smith, Ryan J., Zhang, Hongpan, Hu, Shengen Shawn, Yung, Theodora, Francis, Roshane, Lee, Lilian, Onaitis, Mark W., Dirks, Peter B., Zang, Chongzhi, Kim, Tae-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135761/
https://www.ncbi.nlm.nih.gov/pubmed/35618699
http://dx.doi.org/10.1038/s41467-022-30624-w

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