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Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©)
PURPOSE: The purpose of this prospective study was to assess which nutritional impact symptoms (NIS) interfere with oral intake in patients with head and neck cancer (HNC) and how the symptoms interfere with body weight loss, up to 1 year after treatment. METHODS: This was a prospective study of 197...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135877/ https://www.ncbi.nlm.nih.gov/pubmed/35426524 http://dx.doi.org/10.1007/s00520-022-07038-x |
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author | Granström, Brith Holmlund, Thorbjörn Laurell, Göran Fransson, Per Tiblom Ehrsson, Ylva |
author_facet | Granström, Brith Holmlund, Thorbjörn Laurell, Göran Fransson, Per Tiblom Ehrsson, Ylva |
author_sort | Granström, Brith |
collection | PubMed |
description | PURPOSE: The purpose of this prospective study was to assess which nutritional impact symptoms (NIS) interfere with oral intake in patients with head and neck cancer (HNC) and how the symptoms interfere with body weight loss, up to 1 year after treatment. METHODS: This was a prospective study of 197 patients with HNC planned for treatment with curative intention. Body weight was measured before the start of treatment, at 7 weeks after the start of treatment, and at 6 and 12 months after completion of treatment. NIS and NIS interfering with oral intake at each follow-up were examined with the Head and Neck Patient Symptom Checklist(©) (HNSC(©)). RESULTS: At 7 weeks of follow-up, patients experienced the greatest symptom and interference burden, and 12 months after treatment the NIS scorings had not returned to baseline. One year after treatment, the highest scored NIS to interfere with oral intake was swallowing problems, chewing difficulties, and loss of appetite. At all 3 follow-ups, the total cumulative NIS and NIS interfering with oral intake were associated with body weight loss. Factors increasing the risk for a body weight loss of ≥ 10% at 12 months after treatment were pain, loss of appetite, feeling full, sore mouth, difficulty swallowing, taste changes, and dry mouth. Women scored higher than men in NIS and NIS interfering with oral intake. Furthermore, during the study period about half of the population had a body weight loss > 5%. CONCLUSION: Because both nutritional and clinical factors may affect body weight, this study highlights the importance of a holistic approach when addressing the patients’ nutritional issues. TRIAL REGISTRATION: ClinicalTrials.gov NCT03343236, date of registration: November 17, 2017. |
format | Online Article Text |
id | pubmed-9135877 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-91358772022-05-28 Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) Granström, Brith Holmlund, Thorbjörn Laurell, Göran Fransson, Per Tiblom Ehrsson, Ylva Support Care Cancer Original Article PURPOSE: The purpose of this prospective study was to assess which nutritional impact symptoms (NIS) interfere with oral intake in patients with head and neck cancer (HNC) and how the symptoms interfere with body weight loss, up to 1 year after treatment. METHODS: This was a prospective study of 197 patients with HNC planned for treatment with curative intention. Body weight was measured before the start of treatment, at 7 weeks after the start of treatment, and at 6 and 12 months after completion of treatment. NIS and NIS interfering with oral intake at each follow-up were examined with the Head and Neck Patient Symptom Checklist(©) (HNSC(©)). RESULTS: At 7 weeks of follow-up, patients experienced the greatest symptom and interference burden, and 12 months after treatment the NIS scorings had not returned to baseline. One year after treatment, the highest scored NIS to interfere with oral intake was swallowing problems, chewing difficulties, and loss of appetite. At all 3 follow-ups, the total cumulative NIS and NIS interfering with oral intake were associated with body weight loss. Factors increasing the risk for a body weight loss of ≥ 10% at 12 months after treatment were pain, loss of appetite, feeling full, sore mouth, difficulty swallowing, taste changes, and dry mouth. Women scored higher than men in NIS and NIS interfering with oral intake. Furthermore, during the study period about half of the population had a body weight loss > 5%. CONCLUSION: Because both nutritional and clinical factors may affect body weight, this study highlights the importance of a holistic approach when addressing the patients’ nutritional issues. TRIAL REGISTRATION: ClinicalTrials.gov NCT03343236, date of registration: November 17, 2017. Springer Berlin Heidelberg 2022-04-15 2022 /pmc/articles/PMC9135877/ /pubmed/35426524 http://dx.doi.org/10.1007/s00520-022-07038-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Granström, Brith Holmlund, Thorbjörn Laurell, Göran Fransson, Per Tiblom Ehrsson, Ylva Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) |
title | Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) |
title_full | Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) |
title_fullStr | Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) |
title_full_unstemmed | Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) |
title_short | Addressing symptoms that affect patients’ eating according to the Head and Neck Patient Symptom Checklist(©) |
title_sort | addressing symptoms that affect patients’ eating according to the head and neck patient symptom checklist(©) |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135877/ https://www.ncbi.nlm.nih.gov/pubmed/35426524 http://dx.doi.org/10.1007/s00520-022-07038-x |
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