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SLC4A4, FRAS1, and SULT1A1 Genetic Variations Associated With Dabigatran Metabolism in a Healthy Chinese Population

Background: The purpose of this study was to identify genetic variations associated with the metabolism of dabigatran in healthy Chinese subjects, with particular focus given to pharmacokinetics (PK) and pharmacodynamics (PD). Methods: Healthy Chinese adults aged 18–65 years with unknown genotypes f...

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Detalles Bibliográficos
Autores principales:	Xie, Qiufen, Li, Yuan, Liu, Zhiyan, Mu, Guangyan, Zhang, Hanxu, Zhou, Shuang, Wang, Zhe, Wang, Zining, Jiang, Jie, Li, Xin, Xiang, Qian, Cui, Yimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136018/ https://www.ncbi.nlm.nih.gov/pubmed/35646073 http://dx.doi.org/10.3389/fgene.2022.873031

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