A Network Pharmacology Study: Reveal the Mechanisms of Palovarotene Against Heterotopic Ossification

Heterotopic ossification (HO) occurs when bone forms within non-ossifying tissues, such as in muscle. Palovarotene, an activator of retinoic acid receptor γ (RAR-γ), has been shown to inhibit the formation of ectopic bone in HO model mice, but its specific mechanism of action remains unclear. This s...

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Detalles Bibliográficos
Autores principales: Huang, Junchao, Liu, Dachuan, Zhang, Jingwei, Xiao, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136101/
https://www.ncbi.nlm.nih.gov/pubmed/35646981
http://dx.doi.org/10.3389/fmed.2022.897392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136101/
https://www.ncbi.nlm.nih.gov/pubmed/35646981
http://dx.doi.org/10.3389/fmed.2022.897392

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