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A Network Pharmacology Study: Reveal the Mechanisms of Palovarotene Against Heterotopic Ossification
Heterotopic ossification (HO) occurs when bone forms within non-ossifying tissues, such as in muscle. Palovarotene, an activator of retinoic acid receptor γ (RAR-γ), has been shown to inhibit the formation of ectopic bone in HO model mice, but its specific mechanism of action remains unclear. This s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136101/ https://www.ncbi.nlm.nih.gov/pubmed/35646981 http://dx.doi.org/10.3389/fmed.2022.897392 |