Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series

Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofu...

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Detalles Bibliográficos
Autores principales: Rkieh, Laila, El Nekidy, Wasim S., Alsoud, Leen Oyoun, Alatoom, Adnan, El Lababidi, Rania, Mooty, Mohamad, Nusair, Ahmad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136130/
https://www.ncbi.nlm.nih.gov/pubmed/35646592
http://dx.doi.org/10.1016/j.idcr.2022.e01510
Descripción
Sumario:Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including C. auris. Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.

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