Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series

Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofu...

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Autores principales: Rkieh, Laila, El Nekidy, Wasim S., Alsoud, Leen Oyoun, Alatoom, Adnan, El Lababidi, Rania, Mooty, Mohamad, Nusair, Ahmad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136130/
https://www.ncbi.nlm.nih.gov/pubmed/35646592
http://dx.doi.org/10.1016/j.idcr.2022.e01510
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author Rkieh, Laila
El Nekidy, Wasim S.
Alsoud, Leen Oyoun
Alatoom, Adnan
El Lababidi, Rania
Mooty, Mohamad
Nusair, Ahmad R.
author_facet Rkieh, Laila
El Nekidy, Wasim S.
Alsoud, Leen Oyoun
Alatoom, Adnan
El Lababidi, Rania
Mooty, Mohamad
Nusair, Ahmad R.
author_sort Rkieh, Laila
collection PubMed
description Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including C. auris. Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.
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spelling pubmed-91361302022-05-28 Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series Rkieh, Laila El Nekidy, Wasim S. Alsoud, Leen Oyoun Alatoom, Adnan El Lababidi, Rania Mooty, Mohamad Nusair, Ahmad R. IDCases Case Report Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including C. auris. Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings. Elsevier 2022-05-18 /pmc/articles/PMC9136130/ /pubmed/35646592 http://dx.doi.org/10.1016/j.idcr.2022.e01510 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Rkieh, Laila
El Nekidy, Wasim S.
Alsoud, Leen Oyoun
Alatoom, Adnan
El Lababidi, Rania
Mooty, Mohamad
Nusair, Ahmad R.
Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series
title Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series
title_full Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series
title_fullStr Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series
title_full_unstemmed Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series
title_short Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series
title_sort outcomes of caspofungin use in the treatment of candida-related urinary tract infections, a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136130/
https://www.ncbi.nlm.nih.gov/pubmed/35646592
http://dx.doi.org/10.1016/j.idcr.2022.e01510
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