Metformin Regulates Alveolar Macrophage Polarization to Protect Against Acute Lung Injury in Rats Caused by Paraquat Poisoning

This study explored the role of metformin (MET) in regulating the polarization of alveolar macrophages to protect against acute lung injury (ALI) in rats caused by paraquat (PQ) poisoning. The in vivo studies showed that the 35 mg/kg dose of MET increased the survival rate of rats, alleviated pathol...

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Detalles Bibliográficos
Autores principales: Yuan, Ding, Li, Yi, Hou, Linlin, Yang, Fang, Meng, Cuicui, Yu, Yanwu, Sun, Changhua, Duan, Guoyu, Xu, Zhigao, Zhu, Guiying, Guo, Jianjun, Zhang, Leilei, Yan, Gaiqin, Chen, Jihong, Yang, Yanan, Zhang, Yan, Gao, Yanxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136134/
https://www.ncbi.nlm.nih.gov/pubmed/35645808
http://dx.doi.org/10.3389/fphar.2022.811372

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