Transcriptomic Evidence of the Immune Response Activation in Individuals With Limb Girdle Muscular Dystrophy Dominant 2 (LGMDD2) Contributes to Resistance to HIV-1 Infection

LGMDD2 is a rare form of muscular dystrophy characterized by one of the three heterozygous deletions described within the TNPO3 gene that result in the addition of a 15-amino acid tail in the C-terminus.TNPO3 is involved in the nuclear import of splicing factors and acts as a host cofactor for HIV-1...

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Detalles Bibliográficos
Autores principales: Diez-Fuertes, Francisco, López-Huertas, María Rosa, García-Pérez, Javier, Calonge, Esther, Bermejo, Mercedes, Mateos, Elena, Martí, Pilar, Muelas, Nuria, Vílchez, Juan Jesús, Coiras, Mayte, Alcamí, José, Rodríguez-Mora, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136291/
https://www.ncbi.nlm.nih.gov/pubmed/35646913
http://dx.doi.org/10.3389/fcell.2022.839813

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