Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression

Endosomal trafficking is essential for cellular homeostasis. At the crossroads of distinct intracellular pathways, the endolysosomal system is crucial to maintain critical functions and adapt to the environment. Alterations of endosomal compartments were observed in cells from adult individuals with...

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Detalles Bibliográficos
Autores principales: De Rosa, Laura, Fasano, Dominga, Zerillo, Lucrezia, Valente, Valeria, Izzo, Antonella, Mollo, Nunzia, Amodio, Giuseppina, Polishchuk, Elena, Polishchuk, Roman, Melone, Mariarosa Anna Beatrice, Criscuolo, Chiara, Conti, Anna, Nitsch, Lucio, Remondelli, Paolo, Pierantoni, Giovanna Maria, Paladino, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136301/
https://www.ncbi.nlm.nih.gov/pubmed/35646085
http://dx.doi.org/10.3389/fgene.2022.867989

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