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Closed-state inactivation of cardiac, skeletal, and neuronal sodium channels is isoform specific

Voltage-gated sodium (Nav) channels produce the upstroke of action potentials in excitable tissues throughout the body. The gating of these channels is determined by the asynchronous movements of four voltage-sensing domains (VSDs). Past studies on the skeletal muscle Nav1.4 channel have indicated t...

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Detalles Bibliográficos
Autores principales:	Brake, Niklas, Mancino, Adamo S., Yan, Yuhao, Shimomura, Takushi, Kubo, Yoshihiro, Khadra, Anmar, Bowie, Derek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136305/ https://www.ncbi.nlm.nih.gov/pubmed/35612552 http://dx.doi.org/10.1085/jgp.202112921

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