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Probing function in ligand-gated ion channels without measuring ion transport

Although the functional properties of ion channels are most accurately assessed using electrophysiological approaches, a number of experimental situations call for alternative methods. Here, working on members of the pentameric ligand-gated ion channel (pLGIC) superfamily, we focused on the practica...

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Detalles Bibliográficos
Autores principales: Godellas, Nicole E., Grosman, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136306/
https://www.ncbi.nlm.nih.gov/pubmed/35612603
http://dx.doi.org/10.1085/jgp.202213082