Cargando…

Identification of Transcriptional Heterogeneity and Construction of a Prognostic Model for Melanoma Based on Single-Cell and Bulk Transcriptome Analysis

Melanoma is one of the most aggressive and heterogeneous life-threatening cancers. However, the heterogeneity of melanoma and its impact on clinical outcomes are largely unknown. In the present study, intra-tumoral heterogeneity of melanoma cell subpopulations was explored using public single-cell R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Zijian, Wang, Jing, Huang, Wending, Liu, Jianmin, Yan, Wangjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136400/ https://www.ncbi.nlm.nih.gov/pubmed/35646893 http://dx.doi.org/10.3389/fcell.2022.874429

Ejemplares similares

Identification of Breast Cancer Immune Subtypes by Analyzing Bulk Tumor and Single Cell Transcriptomes
por: Yao, Jia, et al.
Publicado: (2022)

Corrigendum: Identification of breast cancer immune subtypes by analyzing bulk tumor and single cell transcriptomes
por: Yao, Jia, et al.
Publicado: (2022)

Construction and Validation of a Ferroptosis-Related Prognostic Signature for Melanoma Based on Single-Cell RNA Sequencing
por: Liu, Yating, et al.
Publicado: (2022)

Deconvolution of Bulk Gene Expression Profiles with Single-Cell Transcriptomics to Develop a Cell Type Composition-Based Prognostic Model for Acute Myeloid Leukemia
por: Dai, Chengguqiu, et al.
Publicado: (2021)

Identification and Validation of Immune- and Stemness-Related Prognostic Signature of Melanoma
por: Zhang, Yan, et al.
Publicado: (2021)

Identification of Immune Cell Infiltration Landscape and Their Prognostic Significance in Uveal Melanoma
por: Zhao, Han, et al.
Publicado: (2021)

Single cell and bulk transcriptome analysis identified oxidative stress response-related features of Hepatocellular Carcinoma
por: Zhang, Shuqiao, et al.
Publicado: (2023)

Construction and Validation of a Cell Cycle-Related Robust Prognostic Signature in Colon Cancer
por: Zhang, Zhiyuan, et al.
Publicado: (2020)

Identification of a prognostic model using cuproptosis-related genes in uveal melanoma
por: Chen, Yao, et al.
Publicado: (2022)

Development of an Autophagy-Based and Stemness-Correlated Prognostic Model for Hepatocellular Carcinoma Using Bulk and Single-Cell RNA-Sequencing
por: Shen, Shengwei, et al.
Publicado: (2021)

Identification of Hypoxia–Immune-Related Gene Signatures and Construction of a Prognostic Model in Kidney Renal Clear Cell Carcinoma
por: Bai, Shuheng, et al.
Publicado: (2022)

Single-Cell RNA Sequencing With Combined Use of Bulk RNA Sequencing to Reveal Cell Heterogeneity and Molecular Changes at Acute Stage of Ischemic Stroke in Mouse Cortex Penumbra Area
por: Guo, Kang, et al.
Publicado: (2021)

Identification of Epithelial–Mesenchymal Transition-Related Prognostic lncRNAs Biomarkers Associated With Melanoma Microenvironment
por: Xiao, Bo, et al.
Publicado: (2021)

Identification and Validation of Constructing the Prognostic Model With Four DNA Methylation-Driven Genes in Pancreatic Cancer
por: Chen, Guangyu, et al.
Publicado: (2022)

Prognostic Autophagy-Related Model Revealed by Integrating Single-Cell RNA Sequencing Data and Bulk Gene Profiles in Gastric Cancer
por: Tong, Tianying, et al.
Publicado: (2022)

Deeper insights into transcriptional features of cancer-associated fibroblasts: An integrated meta-analysis of single-cell and bulk RNA-sequencing data
por: Kazakova, Anastasia N., et al.
Publicado: (2022)

Deciphering Cell-Type-Specific Gene Expression Signatures of Cardiac Diseases Through Reconstruction of Bulk Transcriptomes
por: Wu, Xiaobin, et al.
Publicado: (2022)

Identification of Precise Therapeutic Targets and Characteristic Prognostic Genes Based on Immune Gene Characteristics in Uveal Melanoma
por: Zhang, Zhenxi, et al.
Publicado: (2021)

Construction and Validation of a Novel Immunosignature for Overall Survival in Uveal Melanoma
por: Gu, Chufeng, et al.
Publicado: (2021)

Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature
por: Wang, Shanhe, et al.
Publicado: (2021)

An update on methods for detection of prognostic and predictive biomarkers in melanoma
por: Adeuyan, Oluwaseyi, et al.
Publicado: (2023)

Cytoskeleton Force Exertion in Bulk Cytoplasm
por: Xie, Jing, et al.
Publicado: (2020)

Construction and Validation of a Novel Pyroptosis-Related Gene Signature to Predict the Prognosis of Uveal Melanoma
por: Cao, Yuan, et al.
Publicado: (2021)

Hypoxia Constructing the Prognostic Model of Colorectal Adenocarcinoma and Related to the Immune Microenvironment
por: Zhang, Yuanyuan, et al.
Publicado: (2021)

Identification and Validation of a Malignant Cell Subset Marker-Based Polygenic Risk Score in Stomach Adenocarcinoma Through Integrated Analysis of Bulk and Single-Cell RNA Sequencing Data
por: Zou, Qiyuan, et al.
Publicado: (2021)

Identification of Differential Gene Groups From Single-Cell Transcriptomes Using Network Entropy
por: Gan, Yanglan, et al.
Publicado: (2020)

Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium
por: Yoshitake, Ryohei, et al.
Publicado: (2022)

Single-nuclei analysis reveals depot-specific transcriptional heterogeneity and depot-specific cell types in adipose tissue of dairy cows
por: Michelotti, Tainara C., et al.
Publicado: (2022)

Construction of a Five-Super-Enhancer-Associated-Genes Prognostic Model for Osteosarcoma Patients
por: Ouyang, Zhanbo, et al.
Publicado: (2020)

Construction of a Prognostic Immune-Related LncRNA Risk Model for Lung Adenocarcinoma
por: Li, Yue, et al.
Publicado: (2021)

Determination of Breast Metabolic Phenotypes and Their Associations With Immunotherapy and Drug-Targeted Therapy: Analysis of Single-Cell and Bulk Sequences
por: Bai, Ming, et al.
Publicado: (2022)

Systematic Construction and Validation of a Prognostic Model for Hepatocellular Carcinoma Based on Immune-Related Genes
por: Yu, Jiahao, et al.
Publicado: (2021)

Corrigendum: Construction of a Five-Super-Enhancer-Associated-Genes Prognostic Model for Osteosarcoma Patients
por: Ouyang, Zhanbo, et al.
Publicado: (2021)

A PARP1-related prognostic signature constructing and PARP-1 inhibitors screening for glioma
por: Li, Hui, et al.
Publicado: (2022)

The Identification of the Metabolism Subtypes of Skin Cutaneous Melanoma Associated With the Tumor Microenvironment and the Immunotherapy
por: Yang, Ronghua, et al.
Publicado: (2021)

Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal Melanoma
por: Sun, Yifang, et al.
Publicado: (2021)

The Landscape of the Tumor Microenvironment in Skin Cutaneous Melanoma Reveals a Prognostic and Immunotherapeutically Relevant Gene Signature
por: Zhou, Sitong, et al.
Publicado: (2021)

The Construction of Bone Metastasis-Specific Prognostic Model and Co-expressed Network of Alternative Splicing in Breast Cancer
por: Huang, Runzhi, et al.
Publicado: (2020)

Construction and Validation of Two Hepatocellular Carcinoma-Progression Prognostic Scores Based on Gene Set Variation Analysis
por: He, Qifan, et al.
Publicado: (2022)

Identification of lncRNA-mRNA Regulatory Module to Explore the Pathogenesis and Prognosis of Melanoma
por: Zhang, Jiaqi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_juohkis92cels53ukohcl8c18e