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GFI1 regulates chromatin state essential in human endothelial‐to‐haematopoietic transition

OBJECTIVES: During embryonic haematopoiesis, haematopoietic stem/progenitor cells (HSPCs) develop from hemogenic endothelial cells (HECs) though endothelial to haematopoietic transition (EHT). However, little is known about how EHT is regulated in human. Here, we report that GFI1 plays an essential...

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Detalles Bibliográficos
Autores principales: Kang, Baoqiang, Zhang, Tian, Huang, Ke, Wang, Tianyu, Li, Yuhang, Mai, Yuchan, Li, Jinbing, Dang, Shiying, Zhang, Zhishuai, Huang, Wenhao, Wang, Junwei, Gao, Minghui, Wang, Yi, Pan, Guangjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136496/
https://www.ncbi.nlm.nih.gov/pubmed/35504619
http://dx.doi.org/10.1111/cpr.13244