Machine learning‐based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small molecule ribosome agonists

OBJECTIVES: To restore tissue growth without increasing the risk for cancer during aging, there is a need to identify small molecule drugs that can increase cell growth without increasing cell proliferation. While there have been numerous high‐throughput drug screens for cell proliferation, there ha...

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Detalles Bibliográficos
Autores principales: Jiang, Zongmin, Zhang, Liping, Yao, Ziyue, Cao, Wenhua, Ma, Shilin, Chen, Yu, Guang, Lu, Zheng, Zipeng, Li, Chunwei, Yu, Kang, Shyh‐Chang, Ng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136510/
https://www.ncbi.nlm.nih.gov/pubmed/35411556
http://dx.doi.org/10.1111/cpr.13214

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