The inhibition of enterocyte proliferation by lithocholic acid exacerbates necrotizing enterocolitis through downregulating the Wnt/β‐catenin signalling pathway

OBJECTIVES: Necrotizing enterocolitis (NEC) is a catastrophic gastrointestinal emergency in preterm infants, whose exact aetiology remains unknown. The role of lithocholic acid (LCA), a key component of secondary bile acids (BAs), in NEC is unclear. METHODS: Clinical data were collected to analyse t...

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Detalles Bibliográficos
Autores principales: Feng, Zhoushan, Jia, Chunhong, Lin, Xiaojun, Hao, Hu, Li, Sitao, Li, Fei, Cui, Qiliang, Chen, Yaoyong, Wu, Fan, Xiao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136529/
https://www.ncbi.nlm.nih.gov/pubmed/35441471
http://dx.doi.org/10.1111/cpr.13228

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