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Self-assembling protein nanocarrier for selective delivery of cytotoxic polypeptides to CXCR4(+) head and neck squamous cell carcinoma tumors
Loco-regional recurrences and distant metastases represent the main cause of head and neck squamous cell carcinoma (HNSCC) mortality. The overexpression of chemokine receptor 4 (CXCR4) in HNSCC primary tumors associates with higher risk of developing loco-regional recurrences and distant metastases,...
Autores principales: | Rioja-Blanco, Elisa, Arroyo-Solera, Irene, Álamo, Patricia, Casanova, Isolda, Gallardo, Alberto, Unzueta, Ugutz, Serna, Naroa, Sánchez-García, Laura, Quer, Miquel, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramon, Alba-Castellón, Lorena, León, Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136533/ https://www.ncbi.nlm.nih.gov/pubmed/35646535 http://dx.doi.org/10.1016/j.apsb.2021.09.030 |
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