Stimuli-responsive nano vehicle enhances cancer immunotherapy by coordinating mitochondria-targeted immunogenic cell death and PD-L1 blockade

Induction of immunogenic cell death promotes antitumor immunity against cancer. However, majority of clinically-approved drugs are unable to elicit sufficient ICD. Here, our study revealed that mitochondria-targeted delivery of doxorubicin (DOX) massively amplified ICD via substantial generation of...

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Detalles Bibliográficos
Autores principales: Li, Qiuyi, Chen, Cheng, Kong, Jinxia, Li, Lian, Li, Junlin, Huang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136536/
https://www.ncbi.nlm.nih.gov/pubmed/35646521
http://dx.doi.org/10.1016/j.apsb.2021.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136536/
https://www.ncbi.nlm.nih.gov/pubmed/35646521
http://dx.doi.org/10.1016/j.apsb.2021.11.005

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