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Stimuli-responsive nano vehicle enhances cancer immunotherapy by coordinating mitochondria-targeted immunogenic cell death and PD-L1 blockade
Induction of immunogenic cell death promotes antitumor immunity against cancer. However, majority of clinically-approved drugs are unable to elicit sufficient ICD. Here, our study revealed that mitochondria-targeted delivery of doxorubicin (DOX) massively amplified ICD via substantial generation of...
Autores principales: | Li, Qiuyi, Chen, Cheng, Kong, Jinxia, Li, Lian, Li, Junlin, Huang, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136536/ https://www.ncbi.nlm.nih.gov/pubmed/35646521 http://dx.doi.org/10.1016/j.apsb.2021.11.005 |
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