Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity

Although the functions of metabolic enzymes and nuclear receptors in controlling physiological homeostasis have been established, their crosstalk in modulating metabolic disease has not been explored. Genetic ablation of the xenobiotic-metabolizing cytochrome P450 enzyme CYP2E1 in mice markedly indu...

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Detalles Bibliográficos
Autores principales: Zhang, Youbo, Yan, Tingting, Wang, Tianxia, Liu, Xiaoyan, Hamada, Keisuke, Sun, Dongxue, Sun, Yizheng, Yang, Yanfang, Wang, Jing, Takahashi, Shogo, Wang, Qiong, Krausz, Kristopher W., Jiang, Changtao, Xie, Cen, Yang, Xiuwei, Gonzalez, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136617/
https://www.ncbi.nlm.nih.gov/pubmed/35646522
http://dx.doi.org/10.1016/j.apsb.2022.02.004

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