Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19

The study involved 271 patients (132 men and 139 women) with moderate COVID-19. Superoxide dismutase (SOD) activity in erythrocytes was measured spectrophotometrically. In total group of patients (divided into age groups of 18-35, 36-45, 46-60, and 61-90 years), higher SOD activity was found in the...

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Autores principales: Semenova, N. V., Rychkova, L. V., Darenskaya, M. A., Kolesnikov, S. I., Nikitina, O. A., Petrova, A. G., Vyrupaeva, E. V., Kolesnikova, L. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136822/
https://www.ncbi.nlm.nih.gov/pubmed/35622260
http://dx.doi.org/10.1007/s10517-022-05491-6
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author Semenova, N. V.
Rychkova, L. V.
Darenskaya, M. A.
Kolesnikov, S. I.
Nikitina, O. A.
Petrova, A. G.
Vyrupaeva, E. V.
Kolesnikova, L. I.
author_facet Semenova, N. V.
Rychkova, L. V.
Darenskaya, M. A.
Kolesnikov, S. I.
Nikitina, O. A.
Petrova, A. G.
Vyrupaeva, E. V.
Kolesnikova, L. I.
author_sort Semenova, N. V.
collection PubMed
description The study involved 271 patients (132 men and 139 women) with moderate COVID-19. Superoxide dismutase (SOD) activity in erythrocytes was measured spectrophotometrically. In total group of patients (divided into age groups of 18-35, 36-45, 46-60, and 61-90 years), higher SOD activity was found in the 18-35 age group in comparison with the groups 46-60 years (p<0.01) and 61-90 years (p<0.05). Then, the groups were additionally divided by sex. In men, no differences in enzyme activity were found between the age groups. In women of early reproductive age, SOD activity was higher than in groups 36-45, 46-60, and 61-90 years. The sex differences consisted in higher SOD activity in women aged 18-35 years in comparison with men of this age. These data should be taken into account when choosing the tactics of therapy for patients with moderate COVID-19 course.
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spelling pubmed-91368222022-06-02 Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19 Semenova, N. V. Rychkova, L. V. Darenskaya, M. A. Kolesnikov, S. I. Nikitina, O. A. Petrova, A. G. Vyrupaeva, E. V. Kolesnikova, L. I. Bull Exp Biol Med Article The study involved 271 patients (132 men and 139 women) with moderate COVID-19. Superoxide dismutase (SOD) activity in erythrocytes was measured spectrophotometrically. In total group of patients (divided into age groups of 18-35, 36-45, 46-60, and 61-90 years), higher SOD activity was found in the 18-35 age group in comparison with the groups 46-60 years (p<0.01) and 61-90 years (p<0.05). Then, the groups were additionally divided by sex. In men, no differences in enzyme activity were found between the age groups. In women of early reproductive age, SOD activity was higher than in groups 36-45, 46-60, and 61-90 years. The sex differences consisted in higher SOD activity in women aged 18-35 years in comparison with men of this age. These data should be taken into account when choosing the tactics of therapy for patients with moderate COVID-19 course. Springer US 2022-05-27 2022 /pmc/articles/PMC9136822/ /pubmed/35622260 http://dx.doi.org/10.1007/s10517-022-05491-6 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Semenova, N. V.
Rychkova, L. V.
Darenskaya, M. A.
Kolesnikov, S. I.
Nikitina, O. A.
Petrova, A. G.
Vyrupaeva, E. V.
Kolesnikova, L. I.
Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19
title Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19
title_full Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19
title_fullStr Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19
title_full_unstemmed Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19
title_short Superoxide Dismutase Activity in Male and Female Patients of Different Age with Moderate COVID-19
title_sort superoxide dismutase activity in male and female patients of different age with moderate covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136822/
https://www.ncbi.nlm.nih.gov/pubmed/35622260
http://dx.doi.org/10.1007/s10517-022-05491-6
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