Fibronectin extra domain A (FN-EDA) causes glaucomatous trabecular meshwork, retina, and optic nerve damage in mice

BACKGROUND: Elevated intraocular pressure (IOP) is a major risk factor for the development and progression of primary open angle glaucoma and is due to trabecular meshwork (TM) damage. Here, we investigate the role of an endogenous Toll-like receptor 4 (TLR4) ligand, FN-EDA, in the development of gl...

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Detalles Bibliográficos
Autores principales: Mavlyutov, Timur A., Myrah, Justin J., Chauhan, Anil K., Liu, Yang, McDowell, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137085/
https://www.ncbi.nlm.nih.gov/pubmed/35619185
http://dx.doi.org/10.1186/s13578-022-00800-y

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