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Intra-Articular Injection of Rebamipide-Loaded Nanoparticles Attenuate Disease Progression and Joint Destruction in Osteoarthritis Rat Model: A Pilot Study

OBJECTIVE: Rebamipide has antioxidant effects and is a drug with a local rather than systemic mechanism of action. Oxidative stress and inflammation in chondrocytes are the major factors contributing to the development and progression of osteoarthritis (OA). Since OA is mainly developed in weight be...

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Detalles Bibliográficos
Autores principales: Kim, Sung Eun, Choi, Sung Jae, Park, Kyeongsoon, Kim, Hak-Jun, Song, Gwan Gyu, Jung, Jae Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137306/
https://www.ncbi.nlm.nih.gov/pubmed/35118894
http://dx.doi.org/10.1177/19476035211069250