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Intra-Articular Injection of Rebamipide-Loaded Nanoparticles Attenuate Disease Progression and Joint Destruction in Osteoarthritis Rat Model: A Pilot Study
OBJECTIVE: Rebamipide has antioxidant effects and is a drug with a local rather than systemic mechanism of action. Oxidative stress and inflammation in chondrocytes are the major factors contributing to the development and progression of osteoarthritis (OA). Since OA is mainly developed in weight be...
Autores principales: | Kim, Sung Eun, Choi, Sung Jae, Park, Kyeongsoon, Kim, Hak-Jun, Song, Gwan Gyu, Jung, Jae Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137306/ https://www.ncbi.nlm.nih.gov/pubmed/35118894 http://dx.doi.org/10.1177/19476035211069250 |
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