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Assessment of Clinical, Tissue, and Cell-Level Metrics Identify Four Biologically Distinct Knee Osteoarthritis Patient Phenotypes

OBJECTIVE: Clinical heterogeneity of primary osteoarthritis (OA) is a major challenge in understanding pathogenesis and development of targeted therapeutic strategies. This study aims to (1) identify OA patient subgroups phenotypes and (2) determine predictors of OA severity and cartilage-derived st...

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Detalles Bibliográficos
Autores principales: Mantripragada, Venkata P., Csorba, Alexander, Bova, Wesley, Boehm, Cynthia, Piuzzi, Nicolas S., Bullen, Jennifer, Midura, Ronald J., Muschler, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137310/
https://www.ncbi.nlm.nih.gov/pubmed/35109693
http://dx.doi.org/10.1177/19476035221074003