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Assessment of Clinical, Tissue, and Cell-Level Metrics Identify Four Biologically Distinct Knee Osteoarthritis Patient Phenotypes
OBJECTIVE: Clinical heterogeneity of primary osteoarthritis (OA) is a major challenge in understanding pathogenesis and development of targeted therapeutic strategies. This study aims to (1) identify OA patient subgroups phenotypes and (2) determine predictors of OA severity and cartilage-derived st...
Autores principales: | Mantripragada, Venkata P., Csorba, Alexander, Bova, Wesley, Boehm, Cynthia, Piuzzi, Nicolas S., Bullen, Jennifer, Midura, Ronald J., Muschler, George F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137310/ https://www.ncbi.nlm.nih.gov/pubmed/35109693 http://dx.doi.org/10.1177/19476035221074003 |
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