Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence

OBJECTIVE: The persistence of auditory, vestibular, olfactory, and gustatory dysfunction for an extended time after COVID-19 has been documented, which represents an emerging challenge of which ENT specialists must be aware. This systematic review aims to evaluate the prevalence of persistent audiov...

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Autores principales: De Luca, Pietro, Di Stadio, Arianna, Colacurcio, Vito, Marra, Pasquale, Scarpa, Alfonso, Ricciardiello, Filippo, Cassandro, Claudia, Camaioni, Angelo, Cassandro, Ettore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137376/
https://www.ncbi.nlm.nih.gov/pubmed/35763279
http://dx.doi.org/10.14639/0392-100X-suppl.1-42-2022-10
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author De Luca, Pietro
Di Stadio, Arianna
Colacurcio, Vito
Marra, Pasquale
Scarpa, Alfonso
Ricciardiello, Filippo
Cassandro, Claudia
Camaioni, Angelo
Cassandro, Ettore
author_facet De Luca, Pietro
Di Stadio, Arianna
Colacurcio, Vito
Marra, Pasquale
Scarpa, Alfonso
Ricciardiello, Filippo
Cassandro, Claudia
Camaioni, Angelo
Cassandro, Ettore
author_sort De Luca, Pietro
collection PubMed
description OBJECTIVE: The persistence of auditory, vestibular, olfactory, and gustatory dysfunction for an extended time after COVID-19 has been documented, which represents an emerging challenge of which ENT specialists must be aware. This systematic review aims to evaluate the prevalence of persistent audiovestibolar and olfactory/gustatory symptoms in patients with “long-COVID”. METHODS: The literature was systematically reviewed according to PRISMA guidelines; PubMed, Scopus and Google Scholar were screened by searching articles on audiovestibular symptoms and olfactory/gustatory dysfunction after SARS-CoV-2 infection. The keywords used were hearing loss, tinnitus, vertigo, smell disorders, parosmia, anosmia, hyposmia, dysgeusia combined with COVID-19 or SARS-CoV-2. RESULTS: 1100 articles were identified. After removal of duplicates (382), 702 articles were excluded, and 16 were included in the systematic review. All articles included identified an association between SARS-CoV-2 infection and persistent hearing or chemosensory impairment. The studies were published over a period of 2 years, between 2019 and 2021. CONCLUSIONS: The likelihood of patients with persistent audiovestibular symptoms related to COVID-19 was different among the articles; however, olfactory and gustatory disturbances were more consistently reported. Studies with longer follow-up are required to fully evaluate the long-term impact of these conditions.
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spelling pubmed-91373762022-06-01 Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence De Luca, Pietro Di Stadio, Arianna Colacurcio, Vito Marra, Pasquale Scarpa, Alfonso Ricciardiello, Filippo Cassandro, Claudia Camaioni, Angelo Cassandro, Ettore Acta Otorhinolaryngol Ital Review OBJECTIVE: The persistence of auditory, vestibular, olfactory, and gustatory dysfunction for an extended time after COVID-19 has been documented, which represents an emerging challenge of which ENT specialists must be aware. This systematic review aims to evaluate the prevalence of persistent audiovestibolar and olfactory/gustatory symptoms in patients with “long-COVID”. METHODS: The literature was systematically reviewed according to PRISMA guidelines; PubMed, Scopus and Google Scholar were screened by searching articles on audiovestibular symptoms and olfactory/gustatory dysfunction after SARS-CoV-2 infection. The keywords used were hearing loss, tinnitus, vertigo, smell disorders, parosmia, anosmia, hyposmia, dysgeusia combined with COVID-19 or SARS-CoV-2. RESULTS: 1100 articles were identified. After removal of duplicates (382), 702 articles were excluded, and 16 were included in the systematic review. All articles included identified an association between SARS-CoV-2 infection and persistent hearing or chemosensory impairment. The studies were published over a period of 2 years, between 2019 and 2021. CONCLUSIONS: The likelihood of patients with persistent audiovestibular symptoms related to COVID-19 was different among the articles; however, olfactory and gustatory disturbances were more consistently reported. Studies with longer follow-up are required to fully evaluate the long-term impact of these conditions. Pacini Editore Srl 2022-04-26 2022-04 /pmc/articles/PMC9137376/ /pubmed/35763279 http://dx.doi.org/10.14639/0392-100X-suppl.1-42-2022-10 Text en Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Review
De Luca, Pietro
Di Stadio, Arianna
Colacurcio, Vito
Marra, Pasquale
Scarpa, Alfonso
Ricciardiello, Filippo
Cassandro, Claudia
Camaioni, Angelo
Cassandro, Ettore
Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
title Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
title_full Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
title_fullStr Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
title_full_unstemmed Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
title_short Long COVID, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
title_sort long covid, audiovestibular symptoms and persistent chemosensory dysfunction: a systematic review of the current evidence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137376/
https://www.ncbi.nlm.nih.gov/pubmed/35763279
http://dx.doi.org/10.14639/0392-100X-suppl.1-42-2022-10
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