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Long March Toward Safe and Effective Analgesia by Enhancing Gene Expression of Kcc2: First Steps Taken
Low intraneuronal chloride in spinal cord dorsal horn pain relay neurons is critical for physiologic transmission of primary pain afferents because low intraneuronal chloride dictates whether GABA-ergic and glycin-ergic neurotransmission is inhibitory. If the neuronal chloride elevates to pathologic...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137411/ https://www.ncbi.nlm.nih.gov/pubmed/35645734 http://dx.doi.org/10.3389/fnmol.2022.865600 |