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The Class A β-Lactamase Produced by Burkholderia Species Compromises the Potency of Tebipenem against a Panel of Isolates from the United States

Tebipenem-pivoxil hydrobromide, an orally bioavailable carbapenem, is currently in clinical development for the treatment of extended-spectrum β-lactamase- and AmpC-producing Enterobacterales. Previously, tebipenem was found to possess antimicrobial activity against the biothreat pathogens, Burkhold...

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Detalles Bibliográficos
Autores principales:	Becka, Scott A., Zeiser, Elise T., LiPuma, John J., Papp-Wallace, Krisztina M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137479/ https://www.ncbi.nlm.nih.gov/pubmed/35625319 http://dx.doi.org/10.3390/antibiotics11050674

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