Cargando…

Local and Global Protein Interactions Contribute to Residue Entrenchment in Beta-Lactamase TEM-1

Due to their rapid evolution and their impact on healthcare, beta-lactamases, protein degrading beta-lactam antibiotics, are used as generic models of protein evolution. Therefore, we investigated the mutation effects in two distant beta-lactamases, TEM-1 and CTX-M-15. Interestingly, we found a site...

Descripción completa

Detalles Bibliográficos
Autores principales:	Birgy, André, Magnan, Mélanie, Hobson, Claire Amaris, Figliuzzi, Matteo, Panigoni, Karine, Codde, Cyrielle, Tenaillon, Olivier, Jacquier, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137480/ https://www.ncbi.nlm.nih.gov/pubmed/35625296 http://dx.doi.org/10.3390/antibiotics11050652

Ejemplares similares

Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1
por: Figliuzzi, Matteo, et al.
Publicado: (2016)

Impact of anticancer chemotherapy on the extension of beta-lactamase spectrum: an example with KPC-type carbapenemase activity towards ceftazidime-avibactam
por: Hobson, Claire Amaris, et al.
Publicado: (2020)

A Microbiota-Dependent Response to Anticancer Treatment in an In Vitro Human Microbiota Model: A Pilot Study With Hydroxycarbamide and Daunorubicin
por: Hobson, Claire Amaris, et al.
Publicado: (2022)

Functional Dynamics of Substrate Recognition in TEM Beta-Lactamase
por: Avery, Chris, et al.
Publicado: (2022)

The Role of Rigid Residues in Modulating TEM-1 β-Lactamase Function and Thermostability
por: Kolbaba-Kartchner, Bethany, et al.
Publicado: (2021)

Organizational Development as Generative Entrenchment
por: Moser, Cody, et al.
Publicado: (2022)

Screening of inhibitors for S130G inhibitor resistant mutants of TEM type beta-lactamase
por: Baig, Mohd Hassan, et al.
Publicado: (2012)

Predicting mutations deleterious to function in beta-lactamase TEM1 using MM-GBSA
por: Negron, Christopher, et al.
Publicado: (2019)

Assessment of Phenotype Relevant Amino Acid Residues in TEM-β-Lactamases by Mathematical Modelling and Experimental Approval
por: Madzgalla, Sara, et al.
Publicado: (2021)

Senescence and entrenchment in evolution of amino acid sites
por: Stolyarova, A. V., et al.
Publicado: (2020)

A hydrophobic ratchet entrenches molecular complexes
por: Hochberg, Georg K.A., et al.
Publicado: (2020)

The Prevalence of TEM and SHV Genes among Extended-Spectrum Beta-Lactamases Producing Escherichia Coli and Klebsiella Pneumoniae
por: Zaniani, Fatemeh Riyahi, et al.
Publicado: (2012)

Prevalence of TEM, SHV, and CTX-M Beta-Lactamase genes in the urinary isolates of a tertiary care hospital
por: Bajpai, Trupti, et al.
Publicado: (2017)

Experimental and In Silico Analysis of TEM β-Lactamase Adaptive Evolution
por: Standley, Melissa, et al.
Publicado: (2022)

The Interactive Construction of Biological Individuality Through Biotic Entrenchment
por: Hernández, Isaac, et al.
Publicado: (2019)

China's rural health reforms tackle entrenched inequalities
por: Watts, Jonathan
Publicado: (2006)

Community faecal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae in french children
por: Birgy, André, et al.
Publicado: (2012)

Horizontol dissemination of TEM- and SHV-typr beta-lactamase genes-carrying resistance plasmids amongst clonical isolates of Enterobacteriaceae
por: Ozgumus, Osman Birol, et al.
Publicado: (2008)

MiniBioReactor Array (MBRA) in vitro gut model: a reliable system to study microbiota-dependent response to antibiotic treatment
por: Hobson, C A, et al.
Publicado: (2022)

Improving measurement-invariance assessments: correcting entrenched testing deficiencies
por: Hayduk, Leslie A.
Publicado: (2016)

Epistasis and entrenchment of drug resistance in HIV-1 subtype B
por: Biswas, Avik, et al.
Publicado: (2019)

Evolutionary entrenchment in immune proteins selects against stabilizing mutations
por: Morcos, Faruck
Publicado: (2022)

Confronting an entrenched atrioventricular node: Ablation strategies for an elusive target
por: Laxina, Ian, et al.
Publicado: (2023)

Molecular Characterization and In Silico Analysis of Naturally Occurring TEM Beta-Lactamase Variants among Pathogenic Enterobacteriaceae Infecting Indian Patients
por: Dhara, Lena, et al.
Publicado: (2013)

The Lactamase Engineering Database: a critical survey of TEM sequences in public databases
por: Thai, Quan Ke, et al.
Publicado: (2009)

Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase
por: Zwart, Mark P., et al.
Publicado: (2018)

Mutations Utilize Dynamic Allostery to Confer Resistance in TEM-1 β-lactamase
por: Modi, Tushar, et al.
Publicado: (2018)

The Role of the Ω-Loop in Regulation of the Catalytic Activity of TEM-Type β-Lactamases
por: Egorov, Alexey, et al.
Publicado: (2019)

The Interplay of Electrostatics and Chemical Positioning in the Evolution of Antibiotic Resistance in TEM β-Lactamases
por: Schneider, Samuel H., et al.
Publicado: (2021)

Mechanical removal of surface residues on graphene for TEM characterizations
por: Kim, Dong-Gyu, et al.
Publicado: (2020)

The Ethics of the Societal Entrenchment-approach and the case of live uterus transplantation-IVF
por: Guntram, Lisa, et al.
Publicado: (2019)

Covalent docking and molecular dynamics simulations reveal the specificity-shifting mutations Ala237Arg and Ala237Lys in TEM beta-lactamase
por: da Silva, Gabriel Monteiro, et al.
Publicado: (2022)

Role of pleiotropy during adaptation of TEM-1 β-lactamase to two novel antibiotics
por: Schenk, Martijn F, et al.
Publicado: (2015)

Recent Increase in the Incidence of TEM-135 β-Lactamase-harboring Neisseria gonorrhoeae in Korea
por: Rim, John Hoon, et al.
Publicado: (2018)

Machine Learning Classification Model for Functional Binding Modes of TEM-1 β-Lactamase
por: Wang, Feng, et al.
Publicado: (2019)

Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 β-Lactamase
por: Knies, Jennifer L., et al.
Publicado: (2017)

Inhibition of Class A β-Lactamase (TEM-1) by Narrow Fractions of Humic Substances
por: Mikhnevich, Tatyana A., et al.
Publicado: (2021)

Antibiotic-Efficient Genetic Cassette for the TEM-1 β-Lactamase That Improves Plasmid Performance
por: Cumming, Alister J., et al.
Publicado: (2022)

Levels of career commitment and career entrenchment of nurses from public and private hospitals
por: Lima, Mauren Pimentel, et al.
Publicado: (2015)

Inference of Epistatic Effects Leading to Entrenchment and Drug Resistance in HIV-1 Protease
por: Flynn, William F., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8e89rjp01593bcgn325a9gj8bl