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Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review

In recent years, a number of bacterial detection methods have been developed to replace time-consuming culture methods. One interesting approach is to mobilize the ability of phage tail proteins to recognize and bind to bacterial hosts. In this paper, the authors provide an overview of the current m...

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Autores principales: Filik, Karolina, Szermer-Olearnik, Bożena, Oleksy, Sabina, Brykała, Jan, Brzozowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137617/
https://www.ncbi.nlm.nih.gov/pubmed/35625199
http://dx.doi.org/10.3390/antibiotics11050555
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author Filik, Karolina
Szermer-Olearnik, Bożena
Oleksy, Sabina
Brykała, Jan
Brzozowska, Ewa
author_facet Filik, Karolina
Szermer-Olearnik, Bożena
Oleksy, Sabina
Brykała, Jan
Brzozowska, Ewa
author_sort Filik, Karolina
collection PubMed
description In recent years, a number of bacterial detection methods have been developed to replace time-consuming culture methods. One interesting approach is to mobilize the ability of phage tail proteins to recognize and bind to bacterial hosts. In this paper, the authors provide an overview of the current methodologies in which phage proteins play major roles in detecting pathogenic bacteria. Authors focus on proteins capable of recognizing highly pathogenic strains, such as Acinetobacter baumannii, Campylobacter spp., Yersinia pestis, Pseudomonas aeruginosa, Listeria monocytogenes, Staphylococcus aureus, Enterococcus spp., Salmonella spp., and Shigella. These pathogens may be diagnosed by capture-based detection methods involving the use of phage protein-coated nanoparticles, ELISA (enzyme-linked immunosorbent assay)-based methods, or biosensors. The reviewed studies show that phage proteins are becoming an important diagnostic tool due to the discovery of new phages and the increasing knowledge of understanding the specificity and functions of phage tail proteins.
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spelling pubmed-91376172022-05-28 Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review Filik, Karolina Szermer-Olearnik, Bożena Oleksy, Sabina Brykała, Jan Brzozowska, Ewa Antibiotics (Basel) Review In recent years, a number of bacterial detection methods have been developed to replace time-consuming culture methods. One interesting approach is to mobilize the ability of phage tail proteins to recognize and bind to bacterial hosts. In this paper, the authors provide an overview of the current methodologies in which phage proteins play major roles in detecting pathogenic bacteria. Authors focus on proteins capable of recognizing highly pathogenic strains, such as Acinetobacter baumannii, Campylobacter spp., Yersinia pestis, Pseudomonas aeruginosa, Listeria monocytogenes, Staphylococcus aureus, Enterococcus spp., Salmonella spp., and Shigella. These pathogens may be diagnosed by capture-based detection methods involving the use of phage protein-coated nanoparticles, ELISA (enzyme-linked immunosorbent assay)-based methods, or biosensors. The reviewed studies show that phage proteins are becoming an important diagnostic tool due to the discovery of new phages and the increasing knowledge of understanding the specificity and functions of phage tail proteins. MDPI 2022-04-21 /pmc/articles/PMC9137617/ /pubmed/35625199 http://dx.doi.org/10.3390/antibiotics11050555 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Filik, Karolina
Szermer-Olearnik, Bożena
Oleksy, Sabina
Brykała, Jan
Brzozowska, Ewa
Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review
title Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review
title_full Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review
title_fullStr Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review
title_full_unstemmed Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review
title_short Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition—A Literature Review
title_sort bacteriophage tail proteins as a tool for bacterial pathogen recognition—a literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137617/
https://www.ncbi.nlm.nih.gov/pubmed/35625199
http://dx.doi.org/10.3390/antibiotics11050555
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