Cardiac NF-κB Acetylation Increases While Nrf2-Related Gene Expression and Mitochondrial Activity Are Impaired during the Progression of Diabetes in UCD-T2DM Rats

The onset of type II diabetes increases the heart’s susceptibility to oxidative damage because of the associated inflammation and diminished antioxidant response. Transcription factor NF-κB initiates inflammation while Nrf2 controls antioxidant defense. Current evidence suggests crosstalk between th...

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Detalles Bibliográficos
Autores principales: Thorwald, Max A., Godoy-Lugo, Jose A., Rodriguez, Ruben, Stanhope, Kimber L., Graham, James L., Havel, Peter J., Forman, Henry Jay, Ortiz, Rudy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137621/
https://www.ncbi.nlm.nih.gov/pubmed/35624791
http://dx.doi.org/10.3390/antiox11050927

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