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Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome

Metabolic syndrome (MetS) is characterized by increased pro-oxidative stress and a pro-inflammatory state. Several studies emphasized the protective effect of the Mediterranean dietary pattern (MDP). To assess the oxidative and inflammatory state according to the adherence to MDP using biomarkers in...

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Autores principales: Quetglas-Llabrés, Maria Magdalena, Monserrat-Mesquida, Margalida, Bouzas, Cristina, Gómez, Cristina, Mateos, David, Ripoll-Vera, Tomàs, Tur, Josep A., Sureda, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137637/
https://www.ncbi.nlm.nih.gov/pubmed/35624765
http://dx.doi.org/10.3390/antiox11050901
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author Quetglas-Llabrés, Maria Magdalena
Monserrat-Mesquida, Margalida
Bouzas, Cristina
Gómez, Cristina
Mateos, David
Ripoll-Vera, Tomàs
Tur, Josep A.
Sureda, Antoni
author_facet Quetglas-Llabrés, Maria Magdalena
Monserrat-Mesquida, Margalida
Bouzas, Cristina
Gómez, Cristina
Mateos, David
Ripoll-Vera, Tomàs
Tur, Josep A.
Sureda, Antoni
author_sort Quetglas-Llabrés, Maria Magdalena
collection PubMed
description Metabolic syndrome (MetS) is characterized by increased pro-oxidative stress and a pro-inflammatory state. Several studies emphasized the protective effect of the Mediterranean dietary pattern (MDP). To assess the oxidative and inflammatory state according to the adherence to MDP using biomarkers in patients with MetS. Antioxidant and pro-inflammatory biomarkers were determined in plasma, peripheral blood mononuclear cells (PBMCs), and neutrophils of adults (aged 55–75 years old; 60% women) with MetS living in Mallorca (Spain). Anthropometrics, dietary intake by a validated semi-quantitative 143-item food frequency questionnaire, and a Dietary Inflammatory Index were measured. Patients with low adherence to MDP showed higher levels of glycated haemoglobin A1c and triglycerides, and lower levels of HDL cholesterol. Plasma levels of interleukin-1β, IL-6, IL-15, tumour necrosis factor α, xanthine oxidase, and ghrelin, and activities of superoxide dismutase, and myeloperoxidase were higher in subjects with low adherence to the MDP. Reactive oxygen species production in PBMCs and neutrophils stimulated with lipopolysaccharide was higher in participants with low adherence to the MDP. Patients with MetS and higher adherence to the MDP showed less altered anthropometric parameters, blood biochemical profile, and better oxidative and inflammatory status.
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spelling pubmed-91376372022-05-28 Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome Quetglas-Llabrés, Maria Magdalena Monserrat-Mesquida, Margalida Bouzas, Cristina Gómez, Cristina Mateos, David Ripoll-Vera, Tomàs Tur, Josep A. Sureda, Antoni Antioxidants (Basel) Article Metabolic syndrome (MetS) is characterized by increased pro-oxidative stress and a pro-inflammatory state. Several studies emphasized the protective effect of the Mediterranean dietary pattern (MDP). To assess the oxidative and inflammatory state according to the adherence to MDP using biomarkers in patients with MetS. Antioxidant and pro-inflammatory biomarkers were determined in plasma, peripheral blood mononuclear cells (PBMCs), and neutrophils of adults (aged 55–75 years old; 60% women) with MetS living in Mallorca (Spain). Anthropometrics, dietary intake by a validated semi-quantitative 143-item food frequency questionnaire, and a Dietary Inflammatory Index were measured. Patients with low adherence to MDP showed higher levels of glycated haemoglobin A1c and triglycerides, and lower levels of HDL cholesterol. Plasma levels of interleukin-1β, IL-6, IL-15, tumour necrosis factor α, xanthine oxidase, and ghrelin, and activities of superoxide dismutase, and myeloperoxidase were higher in subjects with low adherence to the MDP. Reactive oxygen species production in PBMCs and neutrophils stimulated with lipopolysaccharide was higher in participants with low adherence to the MDP. Patients with MetS and higher adherence to the MDP showed less altered anthropometric parameters, blood biochemical profile, and better oxidative and inflammatory status. MDPI 2022-05-01 /pmc/articles/PMC9137637/ /pubmed/35624765 http://dx.doi.org/10.3390/antiox11050901 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Quetglas-Llabrés, Maria Magdalena
Monserrat-Mesquida, Margalida
Bouzas, Cristina
Gómez, Cristina
Mateos, David
Ripoll-Vera, Tomàs
Tur, Josep A.
Sureda, Antoni
Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome
title Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome
title_full Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome
title_fullStr Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome
title_full_unstemmed Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome
title_short Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome
title_sort inflammatory and oxidative stress markers related to adherence to the mediterranean diet in patients with metabolic syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137637/
https://www.ncbi.nlm.nih.gov/pubmed/35624765
http://dx.doi.org/10.3390/antiox11050901
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