Cargando…

NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers

Inflammasomes, particularly the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3 (NLRP3) inflammasome, apparently serve as crucial regulators of the inflammatory response through the activation of Caspase-1 and induction of pro-inflammatory cytokines and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hurtado-Navarro, Laura, Angosto-Bazarra, Diego, Pelegrín, Pablo, Baroja-Mazo, Alberto, Cuevas, Santiago
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137763/ https://www.ncbi.nlm.nih.gov/pubmed/35624734 http://dx.doi.org/10.3390/antiox11050870

Ejemplares similares

Emerging Role of NLRP3 Inflammasome and Pyroptosis in Liver Transplantation
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2022)

Emerging Role of the Inflammasome and Pyroptosis in Hypertension
por: De Miguel, Carmen, et al.
Publicado: (2021)

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles
por: Angosto-Bazarra, Diego, et al.
Publicado: (2022)

Techniques to Study Inflammasome Activation and Inhibition by Small Molecules
por: Angosto-Bazarra, Diego, et al.
Publicado: (2021)

Soluble P2X7 Receptor Is Elevated in the Plasma of COVID-19 Patients and Correlates With Disease Severity
por: García-Villalba, Julio, et al.
Publicado: (2022)

Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation
por: Tapia-Abellán, Ana, et al.
Publicado: (2021)

NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
por: Hafner-Bratkovič, Iva, et al.
Publicado: (2018)

Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure
por: Malhotra, Sunny, et al.
Publicado: (2023)

The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases
por: de Torre-Minguela, Carlos, et al.
Publicado: (2017)

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis
por: Martínez-García, Juan José, et al.
Publicado: (2019)

Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality
por: Angosto-Bazarra, Diego, et al.
Publicado: (2022)

Extracellular ATP Activates the NLRP3 Inflammasome and Is an Early Danger Signal of Skin Allograft Rejection
por: Amores-Iniesta, Joaquín, et al.
Publicado: (2017)

MCC950 closes the active conformation of NLRP3 to an inactive state
por: Tapia-Abellán, Ana, et al.
Publicado: (2019)

Modulating P2X7 Receptor Signaling during Rheumatoid Arthritis: New Therapeutic Approaches for Bisphosphonates
por: Baroja-Mazo, Alberto, et al.
Publicado: (2012)

Pyroptosis in NLRP3 inflammasome-related atherosclerosis
por: Zeng, Xiang, et al.
Publicado: (2022)

Emerging Role of NLRP3 Inflammasome/Pyroptosis in Huntington’s Disease
por: Paldino, Emanuela, et al.
Publicado: (2022)

Lytic cell death induced by melittin bypasses pyroptosis but induces NLRP3 inflammasome activation and IL-1β release
por: Martín-Sánchez, Fátima, et al.
Publicado: (2017)

P2X7 Receptor Activation Impairs Exogenous MHC Class I Oligopeptides Presentation in Antigen Presenting Cells
por: Baroja-Mazo, Alberto, et al.
Publicado: (2013)

NLRP3 inflammasome-induced pyroptosis in digestive system tumors
por: Wen, Jiexia, et al.
Publicado: (2023)

Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling
por: Lin, Yuqing, et al.
Publicado: (2020)

Danger signals released during cold ischemia storage activate NLRP3 inflammasome in myeloid cells and influence early allograft function in liver transplantation
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2022)

Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages
por: Eisfeld, Hannah S., et al.
Publicado: (2021)

The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells
por: Griswold, Andrew R., et al.
Publicado: (2022)

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in diabetic retinopathy
por: Zheng, Xiaoqin, et al.
Publicado: (2023)

Melatonin attenuates high glucose‑induced endothelial cell pyroptosis by activating the Nrf2 pathway to inhibit NLRP3 inflammasome activation
por: Wang, Xuebin, et al.
Publicado: (2023)

Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype
por: Sallman, David A., et al.
Publicado: (2016)

Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis
por: Cai, Yawen, et al.
Publicado: (2022)

NLRP3 inflammasome activation mediates sleep deprivation-induced pyroptosis in mice
por: Fan, Kun, et al.
Publicado: (2021)

Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
por: Mayes-Hopfinger, Lindsey, et al.
Publicado: (2021)

NLRP3 Inflammasome/Pyroptosis: A Key Driving Force in Diabetic Cardiomyopathy
por: Zhang, Lixia, et al.
Publicado: (2022)

Aerobic exercise alleviates pyroptosis-related diseases by regulating NLRP3 inflammasome
por: Hu, Shujuan, et al.
Publicado: (2022)

Astragaloside IV Alleviates Cerebral Ischemia-Reperfusion Injury through NLRP3 Inflammasome-Mediated Pyroptosis Inhibition via Activating Nrf2
por: Xiao, Lan, et al.
Publicado: (2021)

Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD
por: Zeng, Jiamin, et al.
Publicado: (2023)

NLRP3 Inflammasome in the Pathophysiology of Hemorrhagic Stroke: A Review
por: Luo, Yujie, et al.
Publicado: (2019)

The NLRP3 Inflammasome: Relevance in Solid Organ Transplantation
por: Burke, Ryan M., et al.
Publicado: (2021)

Editorial: Inflammation and oxidative stress in vascular and renal disease: role of the inflammasome and pyroptosis
por: De Miguel, Carmen, et al.
Publicado: (2023)

Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway
por: Huang, Cancan, et al.
Publicado: (2020)

Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo
por: Liu, Yuhan, et al.
Publicado: (2021)

NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy
por: Zeng, Cheng, et al.
Publicado: (2020)

NLRP3 inflammasome-mediated cytokine production and pyroptosis cell death in breast cancer
por: Faria, Sara Socorro, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qffip51mqm9pht6e9862182kvv