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Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia

The discovery of a new form of corona-viruses in December 2019, SARS-CoV-2, commonly named COVID-19, has reshaped the world. With health and economic issues at stake, scientists have been focusing on understanding the dynamics of the disease, in order to provide the governments with the best policie...

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Autores principales: Algarni, Abeer D., Ben Hamed, Aws, Hamdi, Monia, Elmannai, Hela, Meshoul, Souham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137965/
https://www.ncbi.nlm.nih.gov/pubmed/35634103
http://dx.doi.org/10.7717/peerj-cs.959
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author Algarni, Abeer D.
Ben Hamed, Aws
Hamdi, Monia
Elmannai, Hela
Meshoul, Souham
author_facet Algarni, Abeer D.
Ben Hamed, Aws
Hamdi, Monia
Elmannai, Hela
Meshoul, Souham
author_sort Algarni, Abeer D.
collection PubMed
description The discovery of a new form of corona-viruses in December 2019, SARS-CoV-2, commonly named COVID-19, has reshaped the world. With health and economic issues at stake, scientists have been focusing on understanding the dynamics of the disease, in order to provide the governments with the best policies and strategies allowing them to reduce the span of the virus. The world has been waiting for the vaccine for more than one year. The World Health Organization (WHO) is advertising the vaccine as a safe and effective measure to fight off the virus. Saudi Arabia was the fourth country in the world to start to vaccinate its population. Even with the new simplified COVID-19 rules, the third dose is still mandatory. COVID-19 vaccines have raised many questions regarding in its efficiency and its role to reduce the number of infections. In this work, we try to answer these question and propose a new mathematical model with five compartments, including susceptible, vaccinated, infectious, asymptotic and recovered individuals. We provide theoretical results regarding the effective reproduction number, the stability of endemic equilibrium and disease free equilibrium. We provide numerical analysis of the model based on the Saudi case. Our developed model shows that the vaccine reduces the transmission rate and provides an explanation to the rise in the number of new infections immediately after the start of the vaccination campaign in Saudi Arabia.
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spelling pubmed-91379652022-05-28 Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia Algarni, Abeer D. Ben Hamed, Aws Hamdi, Monia Elmannai, Hela Meshoul, Souham PeerJ Comput Sci Bioinformatics The discovery of a new form of corona-viruses in December 2019, SARS-CoV-2, commonly named COVID-19, has reshaped the world. With health and economic issues at stake, scientists have been focusing on understanding the dynamics of the disease, in order to provide the governments with the best policies and strategies allowing them to reduce the span of the virus. The world has been waiting for the vaccine for more than one year. The World Health Organization (WHO) is advertising the vaccine as a safe and effective measure to fight off the virus. Saudi Arabia was the fourth country in the world to start to vaccinate its population. Even with the new simplified COVID-19 rules, the third dose is still mandatory. COVID-19 vaccines have raised many questions regarding in its efficiency and its role to reduce the number of infections. In this work, we try to answer these question and propose a new mathematical model with five compartments, including susceptible, vaccinated, infectious, asymptotic and recovered individuals. We provide theoretical results regarding the effective reproduction number, the stability of endemic equilibrium and disease free equilibrium. We provide numerical analysis of the model based on the Saudi case. Our developed model shows that the vaccine reduces the transmission rate and provides an explanation to the rise in the number of new infections immediately after the start of the vaccination campaign in Saudi Arabia. PeerJ Inc. 2022-05-13 /pmc/articles/PMC9137965/ /pubmed/35634103 http://dx.doi.org/10.7717/peerj-cs.959 Text en ©2022 Algarni et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Computer Science) and either DOI or URL of the article must be cited.
spellingShingle Bioinformatics
Algarni, Abeer D.
Ben Hamed, Aws
Hamdi, Monia
Elmannai, Hela
Meshoul, Souham
Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia
title Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia
title_full Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia
title_fullStr Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia
title_full_unstemmed Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia
title_short Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia
title_sort mathematical covid-19 model with vaccination: a case study in saudi arabia
topic Bioinformatics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137965/
https://www.ncbi.nlm.nih.gov/pubmed/35634103
http://dx.doi.org/10.7717/peerj-cs.959
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