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Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin

The intense use and misuse of antibiotics is undoubtedly the main factor associated with the high numbers of antibiotic-resistant pathogenic and commensal bacteria worldwide. In low-income countries, this misuse and overuse is widespread, with great consequences at the personal and global levels. In...

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Autores principales: Dohou, Angèle Modupè, Buda, Valentina Oana, Yemoa, Loconon Achille, Anagonou, Severin, Van Bambeke, Françoise, Van Hees, Thierry, Dossou, Francis Moïse, Dalleur, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137971/
https://www.ncbi.nlm.nih.gov/pubmed/35625261
http://dx.doi.org/10.3390/antibiotics11050617
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author Dohou, Angèle Modupè
Buda, Valentina Oana
Yemoa, Loconon Achille
Anagonou, Severin
Van Bambeke, Françoise
Van Hees, Thierry
Dossou, Francis Moïse
Dalleur, Olivia
author_facet Dohou, Angèle Modupè
Buda, Valentina Oana
Yemoa, Loconon Achille
Anagonou, Severin
Van Bambeke, Françoise
Van Hees, Thierry
Dossou, Francis Moïse
Dalleur, Olivia
author_sort Dohou, Angèle Modupè
collection PubMed
description The intense use and misuse of antibiotics is undoubtedly the main factor associated with the high numbers of antibiotic-resistant pathogenic and commensal bacteria worldwide. In low-income countries, this misuse and overuse is widespread, with great consequences at the personal and global levels. In the context of user fee exemptions in caesarean sections, we performed a descriptive study in women to assess the use of antibiotics on three levels—antenatal, during caesarean section, and postpartum—in four Beninese hospitals. Out of the 141 women included, 56.7% were using antibiotics. More than the half (71.3%) were taking more than one antibiotic, either for a long time or in acute treatment. In prophylaxis, the timing, dose, and duration of administration were not correctly achieved. Only 31.2% of women received optimal antibiotic prophylaxis. Various antibiotics including broad-spectrum molecules were used in the patients after caesarean section. The use of antibiotics was improper on the three levels studied. The high rate of self-administered antibiotics, the poor achievement of antibiotic prophylaxis, and the postpartum overuse of antibiotics showed a poor quality of care provided in pregnancy. A national policy is essential to improve the use of antibiotics by the general public as well as by professionals.
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spelling pubmed-91379712022-05-28 Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin Dohou, Angèle Modupè Buda, Valentina Oana Yemoa, Loconon Achille Anagonou, Severin Van Bambeke, Françoise Van Hees, Thierry Dossou, Francis Moïse Dalleur, Olivia Antibiotics (Basel) Article The intense use and misuse of antibiotics is undoubtedly the main factor associated with the high numbers of antibiotic-resistant pathogenic and commensal bacteria worldwide. In low-income countries, this misuse and overuse is widespread, with great consequences at the personal and global levels. In the context of user fee exemptions in caesarean sections, we performed a descriptive study in women to assess the use of antibiotics on three levels—antenatal, during caesarean section, and postpartum—in four Beninese hospitals. Out of the 141 women included, 56.7% were using antibiotics. More than the half (71.3%) were taking more than one antibiotic, either for a long time or in acute treatment. In prophylaxis, the timing, dose, and duration of administration were not correctly achieved. Only 31.2% of women received optimal antibiotic prophylaxis. Various antibiotics including broad-spectrum molecules were used in the patients after caesarean section. The use of antibiotics was improper on the three levels studied. The high rate of self-administered antibiotics, the poor achievement of antibiotic prophylaxis, and the postpartum overuse of antibiotics showed a poor quality of care provided in pregnancy. A national policy is essential to improve the use of antibiotics by the general public as well as by professionals. MDPI 2022-05-04 /pmc/articles/PMC9137971/ /pubmed/35625261 http://dx.doi.org/10.3390/antibiotics11050617 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dohou, Angèle Modupè
Buda, Valentina Oana
Yemoa, Loconon Achille
Anagonou, Severin
Van Bambeke, Françoise
Van Hees, Thierry
Dossou, Francis Moïse
Dalleur, Olivia
Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin
title Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin
title_full Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin
title_fullStr Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin
title_full_unstemmed Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin
title_short Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin
title_sort antibiotic usage in patients having undergone caesarean section: a three-level study in benin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137971/
https://www.ncbi.nlm.nih.gov/pubmed/35625261
http://dx.doi.org/10.3390/antibiotics11050617
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