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Administration of Glutaredoxin-1 Attenuates Liver Fibrosis Caused by Aging and Non-Alcoholic Steatohepatitis

Liver fibrosis is a sign of non-alcoholic fatty liver disease progression towards steatohepatitis (NASH) and cirrhosis and is accelerated by aging. Glutaredoxin-1 (Glrx) controls redox signaling by reversing protein S-glutathionylation, induced by oxidative stress, and its deletion causes fatty live...

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Detalles Bibliográficos
Autores principales:	Tsukahara, Yuko, Ferran, Beatriz, Minetti, Erika T., Chong, Brian S. H., Gower, Adam C., Bachschmid, Markus M., Matsui, Reiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138033/ https://www.ncbi.nlm.nih.gov/pubmed/35624731 http://dx.doi.org/10.3390/antiox11050867

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