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Administration of Glutaredoxin-1 Attenuates Liver Fibrosis Caused by Aging and Non-Alcoholic Steatohepatitis
Liver fibrosis is a sign of non-alcoholic fatty liver disease progression towards steatohepatitis (NASH) and cirrhosis and is accelerated by aging. Glutaredoxin-1 (Glrx) controls redox signaling by reversing protein S-glutathionylation, induced by oxidative stress, and its deletion causes fatty live...
Autores principales: | Tsukahara, Yuko, Ferran, Beatriz, Minetti, Erika T., Chong, Brian S. H., Gower, Adam C., Bachschmid, Markus M., Matsui, Reiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138033/ https://www.ncbi.nlm.nih.gov/pubmed/35624731 http://dx.doi.org/10.3390/antiox11050867 |
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