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Diclofenac: A Nonsteroidal Anti-Inflammatory Drug Inducing Cancer Cell Death by Inhibiting Microtubule Polymerization and Autophagy Flux

Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammatory diseases induces cellular toxicity by increasing the production of reactive oxygen species (ROS) and impairing autophagic flux. In this study, we investigated whether diclofenac induces cancer cell death and the mec...

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Detalles Bibliográficos
Autores principales: Choi, Soohee, Kim, Suree, Park, Jiyoung, Lee, Seung Eun, Kim, Chaewon, Kang, Dongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138099/
https://www.ncbi.nlm.nih.gov/pubmed/35624874
http://dx.doi.org/10.3390/antiox11051009