Cargando…

Endothelial Cell Protein Targeting by Myeloperoxidase-Derived 2-Chlorofatty Aldehyde

Neutrophils are important cellular mediators of injury and repair in diseases including ischemic heart disease, atherosclerosis, and sepsis. Myeloperoxidase-derived (MPO)-oxidants released from neutrophils are potential mediators of endothelial injury in disease. MPO-derived HOCl attacks plasmalogen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shakya, Shubha, Herr, Roger A., Carlson, Haley L., Zoeller, Raphael A., Albert, Carolyn J., Ford, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138145/ https://www.ncbi.nlm.nih.gov/pubmed/35624804 http://dx.doi.org/10.3390/antiox11050940

Ejemplares similares

Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes
por: Shakya, Shubha, et al.
Publicado: (2022)

2-Chlorofatty Aldehyde Elicits Endothelial Cell Activation
por: McHowat, Jane, et al.
Publicado: (2020)

Characterization of N-Acetyl Cysteine Adducts with Exogenous and Neutrophil-Derived 2-Chlorofatty Aldehyde
por: Shakya, Shubha, et al.
Publicado: (2023)

Serum α-chlorofatty acid as a biomarker for baseline subclinical cardiovascular disease in systemic lupus erythematosus
por: Mahieu, MA, et al.
Publicado: (2012)

Neutrophil Myeloperoxidase Derived Chlorolipid Production During Bacteria Exposure
por: Amunugama, Kaushalya, et al.
Publicado: (2021)

Neutrophil-derived microparticles induce myeloperoxidase-mediated damage of vascular endothelial cells
por: Pitanga, Thassila Nogueira, et al.
Publicado: (2014)

Endothelial Function in a Mouse Model of Myeloperoxidase Deficiency
por: Golubinskaya, Veronika, et al.
Publicado: (2014)

Myeloperoxidase: Regulation of Neutrophil Function and Target for Therapy
por: Rizo-Téllez, Salma A., et al.
Publicado: (2022)

Cytotoxicity towards human endothelial cells, induced by neutrophil myeloperoxidase: protection by ceftazidime
por: Mathy-Hartert, M., et al.
Publicado: (1995)

Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
por: Abdo, Adrian I., et al.
Publicado: (2017)

Effect of myeloperoxidase modified LDL on bovine and human aortic endothelial cells
por: El Samad, Ghadir, et al.
Publicado: (2019)

Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice
por: Koop, Anja Christina, et al.
Publicado: (2020)

Myeloperoxidase: a new target for the treatment of stroke?
por: Wang, Yun-Chang, et al.
Publicado: (2022)

Identification of novel neutrophil very long chain plasmalogen molecular species and their myeloperoxidase mediated oxidation products in human sepsis
por: Amunugama, Kaushalya, et al.
Publicado: (2021)

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
por: Davies, Michael J.
Publicado: (2011)

Boronate-Based Oxidant-Responsive Derivatives of Acetaminophen as Proinhibitors of Myeloperoxidase
por: Pierzchała, Karolina, et al.
Publicado: (2023)

Myeloperoxidase in Health and Disease
por: Ortiz-Cerda, Tamara, et al.
Publicado: (2023)

Endothelial Aldehyde Dehydrogenase 2 as a Target to Maintain Vascular Wellness and Function in Ageing
por: Nannelli, Ginevra, et al.
Publicado: (2020)

Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells
por: Rees, Martin D., et al.
Publicado: (2012)

Neutrophil-Derived Myeloperoxidase Facilitates Both the Induction and Elicitation Phases of Contact Hypersensitivity
por: Strzepa, Anna, et al.
Publicado: (2021)

Exposure of Endothelial Cells to Physiological Levels of Myeloperoxidase-Modified LDL Delays Pericellular Fibrinolysis
por: Zouaoui Boudjeltia, Karim, et al.
Publicado: (2012)

Myeloperoxidase and related biomarkers are suggestive footprints of endothelial microvascular inflammation in HFpEF patients
por: Hage, Camilla, et al.
Publicado: (2020)

The Resurrection of Myeloperoxidase as a Therapeutic Target: Is it Lazarus or Just an Apparition?
por: Taylor, Angela M.
Publicado: (2016)

Evaluation of Myeloperoxidase as Target for Host-Directed Therapy in Tuberculosis In Vivo
por: Linnemann, Lara C., et al.
Publicado: (2022)

Myeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective
por: Florez-Barros, Fernanda, et al.
Publicado: (2023)

Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
por: Guo, Chaorui, et al.
Publicado: (2020)

The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages
por: Love, Dominic T., et al.
Publicado: (2020)

Myeloperoxidase inhibition may protect against endothelial glycocalyx shedding induced by COVID-19 plasma
por: Teo, Andrew, et al.
Publicado: (2023)

A myeloperoxidase precursor, pro-myeloperoxidase, is present in human plasma and elevated in cardiovascular disease patients
por: Khalilova, Irada S., et al.
Publicado: (2018)

Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN(−))
por: Vanichkitrungruang, Siriluck, et al.
Publicado: (2020)

Myeloperoxidase-Derived Oxidants Induce Blood-Brain Barrier Dysfunction In Vitro and In Vivo
por: Üllen, Andreas, et al.
Publicado: (2013)

Fluorescent probes for monitoring myeloperoxidase-derived hypochlorous acid: a comparative study
por: Pierzchała, Karolina, et al.
Publicado: (2022)

Myeloperoxidase is not a good biomarker for preeclampsia prediction
por: Rocha-Penha, L., et al.
Publicado: (2017)

Myeloperoxidase Inhibition Ameliorates Plaque Psoriasis in Mice
por: Neu, Savannah D., et al.
Publicado: (2021)

Interaction of aldehydes derived from lipid peroxidation and membrane proteins
por: Pizzimenti, Stefania, et al.
Publicado: (2013)

Impact of myeloperoxidase dosage in acute coronary syndrome
por: Esporcatte, R, et al.
Publicado: (2005)

Myeloperoxidase-Oxidized LDL Activates Human Aortic Endothelial Cells through the LOX-1 Scavenger Receptor
por: El-Hajjar, Layal, et al.
Publicado: (2022)

Contribution of Aldehydes and Their Derivatives to Antimicrobial and Immunomodulatory Activities
por: Aljaafari, Mariam Nasser, et al.
Publicado: (2022)

Preparation and Physicochemical Characterization of Gelatin–Aldehyde Derivatives
por: El-Meligy, Mahmoud Atya, et al.
Publicado: (2022)

Levels of IL-8 and myeloperoxidase in the lungs of pneumonia patients
por: Abul, H., et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_m8p3l7u4mln0t5dahbvgps4gef